The Marshall Lab is part of the
Division of Biomaterials and Bioengineering in the UCSF Department of
Preventive and Restorative Dental Sciences. We conduct a broad range
of laboratory and clinical research in areas related to biomaterials
development, calcified tissues, adhesive dentistry, and implant coatings.
We collaborate extensively with scientists at Lawrence Berkeley National
Lab and Lawrence Livermore National Lab, including high resolution xray tomography for imaging calcified tissues at the
new Advanced Light Source at LBNL. Our current studies on calcified
tissues include studies of the
structure-property relations in dental hard tissues; natural calcified
tissue interfaces, the evaluation of biomechanics and fracture
mechanisms, novel interfacial morphologies for adhesion of calcified
tissues and materials; and the use of transgenic mouse models for tissue
engineering. We have developed a number of innovative methods based on
atomic force microscopy for studying calcified tissues. We also
collaborate with LBNL on the development of new bioactive glasses that may
be useful for implant coatings.
Our lab team includes faculty, visiting scholars, post-docs, graduate
students, and staff members.
We participate in the Oral and Craniofacial Sciences and the UCSF/UCB Joint Bioengineering gradute groups, as well as new UCSF programs in
Craniofacial and Mesenchymal Biology and Biomaterials,
Biophysical Sciences and Engineering.